All-on-4种植修复中倾斜种植体与轴向种植体失败率及边缘骨丧失的比较：meta分析

摘要/Abstract

摘要： 目的　比较All-on-4种植修复中倾斜种植体与轴向种植体随访3年以上的种植体失败率及边缘骨丧失情况。方法　在PubMed、Web of Science、Cochrane Library进行系统检索，手工检索纳入文献的参考文献作为电子检索的补充。检索时间自建库至2019年8月。经过文献筛选和数据提取，进行meta分析。本研究的主要结局为种植体失败率，次要结局为种植体周围边缘骨丧失。结果　12项研究符合纳入标准。结果显示，All-on-4种植修复中倾斜种植体与轴向种植体在种植体失败率上无显著差异（RR=1.24, 95% CI:［0.85, 1.83］, P=0.27）。在种植体周围边缘骨丧失方面，meta分析结果显示All-on-4种植修复中倾斜种植体与轴向种植体之间无显著差异（MD=-0.02, 95% CI:［-0.07, 0.03］, P=0.47）。结论　随访3年以上，All-on-4种植修复中倾斜种植体与轴向种植体具有相似的失败率及边缘骨丧失量。未来需要更多长期随访的高质量研究对本研究结果进行进一步佐证。

关键词: All-on-4, 倾斜种植体, 轴向种植体, meta分析

Abstract: Objective　To compare the implant failure rates and peri-implant marginal bone loss(MBL) of tilted implants and axial implants in All-on-4 treatment concept after over 3-year follow-up. Methods　An electronic search was undertaken in PubMed, Web of Science and Cochrane Library with the searching time from the establishment of the database to August 2019. An additional manual search of the related reviews was also undertaken. After study selection and data extraction, a meta-analysis was conducted. The primary outcome was implant failure rates and the secondary outcome was MBL. Results　Twelve studies meeting the criteria were included. There was no significant difference in implant failure rates(RR=1.24, 95% CI:［0.85, 1.83］, P=0.27) between tilted implants and axial implants in All-on-4 treatment concept. In terms of MBL, meta-analysis showed that no significant difference was found between tilted implants and axial implants(MD=-0.02, 95% CI:［-0.07, 0.03］, P=0.47). Conclusion　After over 3-year follow-up, tilted implants and axial implants in All-on-4 treatment concept might have similar implant failure rates and peri-implant marginal bone loss. More high-quality studies with larger sample size and longer follow-up are needed to support our findings in the future.

Key words: All-on-4, tilted implants, axial implants, meta-analysis

中图分类号:

R782.13

姚立敏杨萌童昕. All-on-4种植修复中倾斜种植体与轴向种植体失败率及边缘骨丧失的比较：meta分析[J]. 口腔医学, 2021, 41(1): 63-70.

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