牙周炎和慢性阻塞性肺疾病间共同危险因素及相关机制研究进展

摘要/Abstract

摘要： 慢性阻塞性肺疾病和牙周病两者都是感染引起的慢性炎症反应性疾病，两者的临床表现均涉及结缔组织的破坏。该文就两者的流行病学情况、共同危险因素、相关的生物学机制的研究进展进行综述。文献复习结果表明牙周炎与慢性阻塞性肺疾病两者之间可相互影响，感染细菌同源性，炎症因子和中性粒细胞都参与了两种疾病的过程，两者的共同危险因素有年龄增长、社会经济状况差、吸烟等，但仍需进一步研究来明确牙周炎和慢性阻塞性肺疾病之间相互作用的具体机制。

关键词: 牙周炎, 慢性阻塞性肺疾病, 流行病学, 炎性因子, 细菌, 中性粒细胞, 基质金属蛋白酶

Abstract: Both chronic obstructive pulmonary disease and periodontal disease are chronic inflammatory diseases caused by infection, and the clinical manifestations of both involve the destruction of connective tissue. This article reviews the epidemiological situation, common risk factors, and related biological mechanisms of the two. Literature review results show that periodontitis and chronic obstructive pulmonary disease can influence each other. The homology of infection bacteria, inflammatory factors and neutrophil inflammation are all involved in the process of the two diseases, and the common risk factors for both There are aging, poor socioeconomic status, smoking, etc., but further research is needed to clarify the specific mechanism of the interaction between periodontitis and chronic obstructive pulmonary disease.

Key words: Periodontitis, Chronic Obstructive Pulmonary Disease, Epidemiology, Inflammatory cytokines, Bacteria, Neutrophils, Matrix metalloproteinase

中图分类号:

R781.42

周政权林晓萍. 牙周炎和慢性阻塞性肺疾病间共同危险因素及相关机制研究进展[J]. 口腔医学, 2021, 41(4): 351-355.

Zheng-Quan ZHOU. Research progress on common risk factors for periodontitis and chronic obstructive pulmonary disease and related mechanisms[J]. Stomatology, 2021, 41(4): 351-355.

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