牙周炎和胎膜早破的关系及其炎症介质的研究进展

摘要/Abstract

摘要： 牙周炎是一种慢性感染性疾病，通常伴有局部或全身的炎症介质变化或免疫环境紊乱，在临床上与多种全身性疾病密切相关。胎膜早破是一种以羊膜内感染为主要因素的疾病，最终以胎膜胶原蛋白破坏，胎膜弱化破裂为结局。近年来，研究者们发现牙周炎和胎膜早破存在一定的相关性，但其中具体的相关机制尚不清楚。该文搜集资料并归纳了与二者相关的多种因素，如微生物、炎症因子和氧化应激等，以求为二者相关性的机制提供一定参考。

关键词: 牙周炎, 胎膜早破, 微生物, 炎症因子, 氧化应激

Abstract: Periodontitis is a chronic infectious disease, usually accompanied by local or systemic inflammatory mediators fluctuation or immune environment disorders. It is clinically related to a variety of systemic diseases. Premature rupture of membranes is a kind of disease with amniotic membrane infection as the main factor, and the destruction of membrane collagen and the weakening and rupture of membrane as the final outcome. In recent years, researchers have found a certain correlation between periodontitis and premature rupture of membranes, but the specific mechanism is unclear. Therefore, this article collects and summarizes a variety of factors related to them, such as microorganisms, inflammatory mediators and oxidative stress, in order to provide some reference for researches on the mechanism of their correlation. 

Key words: periodontitis, premature rupture of membranes, microorganisms, inflammatory mediators, oxidative stress

中图分类号:

R781.42

齐帅林晓萍. 牙周炎和胎膜早破的关系及其炎症介质的研究进展[J]. 口腔医学, 2021, 41(5): 465-469.

Shuai QI. Progress of research on the relationship and inflammatory mediators between periodontitis and premature rupture of membranes[J]. Stomatology, 2021, 41(5): 465-469.

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