口腔医学 ›› 2026, Vol. 46 ›› Issue (1): 66-69.doi: 10.13591/j.cnki.kqyx.2026.01.011

• 病案分析 • 上一篇    下一篇

腮腺Mikulicz病1例及文献回顾

柴丛娜, 焦建军, 程磊(), 靳书滨, 石光   

  1. 河北省邯郸市中心医院口腔科,河北邯郸(056000)
  • 收稿日期:2024-11-12 出版日期:2026-01-28 发布日期:2026-01-16
  • 通讯作者: 程磊 E-mail:275559195@qq.com

Mikulicz disease of the parotid gland: A case report and literature review

CHAI Congna, JIAO Jianjun, CHENG Lei(), JIN Shubin, SHI Guang   

  1. Department of Stomatology, Handan Central Hospital, Handan 056000, China
  • Received:2024-11-12 Online:2026-01-28 Published:2026-01-16
  • Contact: CHENG Lei E-mail:275559195@qq.com

摘要:

Mikulicz病是IgG4相关性疾病,是一种少见的全身性免疫介导的纤维性炎性疾病,其诊断和治疗复杂,目前对其研究较少,容易误诊,这种少见疾病早期诊断和治疗可以防止后期疾病纤维化造成的器官损害。现报道我院收治的1例腮腺Mikulicz病并进行文献回顾,对该疾病的概念、发展过程、诊断和治疗进行讨论,以期提高临床医生对该疾病的认识。

关键词: Mikulicz病, 免疫球蛋白(IgG4)相关疾病, 涎腺肿瘤

Abstract:

Mikulicz disease is an IgG4 related disease and a rare systemic immune-mediated fibrotic disease. Its diagnosis and treatment are complex, and there is currently limited research on it, making it prone to misdiagnosis. Early diagnosis and treatment of this rare disease can prevent organ damage caused by fibrosis in later stages. We report a case of Mikulicz disease of the parotid gland admitted to our hospital and conduct a literature review to discuss the concept, development process, diagnosis, and treatment of this disease, in order to improve clinical doctors’ understanding of this disease.

Key words: Mikulicz disease, immunoglobulin (IgG4)related diseases, salivary gland tumors

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