大鼠正畸牙移动中牙周组织Wnt10b和β-catenin的表达研究

Abstract

Abstract: Abstact：Objective: To investigate the expression of Wnt10b and β-catenin in periodontal tissue during experimental tooth movement in rats. Materials and Methods: 30 Sprague-Dawley (SD) rats’ left maxillary molars movement models were established. The right maxillary molars without force application served as control. At 1, 3, 5, 7, 10, and 14 days after force application, the rats were sacrificed. Immunohistochemical staining was used to investigate the expression of Wnt10b and β-catenin in rats periodontal tissue. Results: The expression of Wnt10b and β-catenin was weak in the periodontal tissue of the control group. In the experimental group, β-catenin expression was significantly higher on both sides at every time point, and Wnt10b expression was significantly higher on both sides at 5, 7, and 10 days. Conclusions: These results indicate that Wnt10b and β-catenin play an important role during periodontal tissue remodeling of orthodontic tooth movement.

Key words: Wnt10b, β-catenin, Orthodontic tooth movement, Periodontal tissue remodeling

CLC Number:

R783.5

References

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The expression of Wnt10b and β-catenin in periodontal tissue during orthodontic tooth movement in rats

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