Abstract: ObjectiveTo study the clinical multifocal Warthin tumor. Methods The clinical and pathological data of 117 Warthin tumor cases in our hospital from July, 2004 to February, 2014were analyzed retrospectively.The cases were divided into “single” group and “multiple” group (unilateral and / or bilateral multifocal) and differences between two groups in gender, age, smoking index, etc., were statistically analyzed. ResultsIn all the 117 cases with Warthin tumor, there were 94 cases in the “single” group, and 23 cases in the “multiple” group; No significant difference was found between the two groups in gender and age (P > 0.05); Smoking rate of the “multiple” group was 95% (22/23), and heavy smoking (smoking index ≥ 400) rate was 73% (17/23), while smoking rate of the“single” group was 75%, and heavy smoking rate was 40%. Statistical analysis showed that the rates of smoking and heavy smoking were significantly higher in the“multiple” group than those inthe “single”group (P< 0.01). ConclusionThe risk of multiple Warthin tumor was closely correlated with smoking and the degree of smoking.

Key words: Warthin tumor, multiple, Smoking index