Abstract: Objective To compare the therapeutic efficacy of the matchedtaper single cone obturation, warm guttapercha Beefill 2 in 1 and the cold lateral condensation. Methods 180 patients were randomly divided into group A, B, C, each containing 60 patients (60 teeth), and were treated with the cold lateral condensation, the warm guttapercha Beefill 2 in 1 and the matchedtaper single cone obturation, respectively. The obturation time, postoperative pain, filling fitness rate, incidence of vertical root fracture, and success rate of obturation were observed. Results The obturation time of group C was （62.6±7.2）s, shorter than that in the other two groups(P＜0.01). Occurrence rate of postoperative pain in group C was 1.67%, lower than that in the other two groups(P＜0.05). Filling fitness rate in group C was 98.33%, higher than that in the other two groups (P＜0.05). The incidence of vertical root fracture in group C was low. Success rate of obturation in group C (96.61%) showed no significant difference compared with the other two groups (P>0.05). Conclusion Given its high curative effect, short operation time, and low incidence of tooth fracture, matched taper single cone obturation is worthy of clinical application.

Key words: the matched –taper single cone obturation technique , warm gutta-ercha Beefill 2 in 1 technique, cold lateral condensation technique, root canal treatment