Abstract: Objective　 To study the effect of minimally invasive tooth extraction in rats. Methods Twenty SD female rats were randomly divided into two groups，the left six molars were extracted by conventional methods(control group) and minimally invasive method(experimental group) respectively. Postoperative survival rates, teeth intactness and the injury of soft tissue in extraction sites were observed. Results Compared with control group, the rat survival rates increased in experimental group, the incidence of crown and root fracture decreased, and the degree of soft tissue injury in dental sockets were milder than the control group. Conclusion The minimally invasive extraction method can effectively save time and resources of animal experiments, which can ensure the following experiments to carry on smoothly.

Key words: animal model, extraction, micro-invasive, rats