Abstract: Abstract: Objective To analyze the anesthesia effect of compound articaine on children's dental pain, and provide reference for clinical anesthesia. Methods 160 children who were treated with gums painless dental anesthesia in hospital from May 2015 to October 2015 were selected, then patients were divided into observation group (80 cases)and control group(80 cases). Observation group patients were taken clinical anesthesia of compound articaine anesthesia, while control group patients were taken clinical anesthesia of Procaine hydrochloride anesthesia, and anesthetic effects of patients were compared. Results Total effective rate of anesthesia of observation group (97.6%) was significantly higher than control group(83.7%), P <0.05, painless rate of the observation group (80.0%) was significantly higher than control group(57.5%), P <0.05, both before and after anesthesia heart rates of two groups had no significant changes, P> 0.05. Conclusion In children's dental gums painless anesthesia, the anesthetic effect of compound articaine is significant and can be improved, with a promotional value.