Abstract: As a global epidemic, obesity is higly correlated with certain systemic diseases such as diabetes, hypertension, cardiovascular disease, etc., and particularly has a close correlation with periodontitis. Adipose tissue can secrete a series of adipocytokines, such as visfatin, leptin, resistin, adiponectin, etc., and it also exists in the cells of periodontal tissue. Adipokines can not only regulate the sensitivity of insulin but also participate in body's inflammatory response, therefore, these two diseases may be linked by adipokines. This review focuses on the effects of adipokines on periodontitis.

Key words: obesity, adipocytokines, periodontitis