›› 2017, Vol. 37 ›› Issue (11): 1029-1033.

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Effects of combined application of BMP-2 with other growth factors on bone regeneration

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  • Received:2017-04-12 Revised:2017-05-10 Online:2017-11-28 Published:2017-11-24

Abstract:  With the development of tissue engineering, more and more growth factors are applied to the reconstruction and regeneration of bone tissue in tissue engineering. Bone morphogenetic protein 2 (BMP-2) is the most common growth factor which is used to promote osteogenic differentiation and bone regeneration. Currently, the combined application of BMP-2 with other factors is becoming a research hotspot. This paper mainly introduces the effect and mechanism of combined application of BMP-2 with other factors.

Key words: Tissue engineering, bone regeneration, bone morphogenetic protein 2, basic fibroblast growth factor, combined application

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