Abstract: Abstract: Periodontitis often leads to periodontal bone defect, which is an urgent problem to be solved in clinic. Traditional scaffolds have made some progress in periodontal regeneration, but still with many limitations. Since the mesoporous materials are characterized by their unique physicochemical properties as uniform pore sizes, high porosity and surface area, which have a rather prosperous prospect compared with the nano materials. As mentioned above, more emphasis has been laid on the application of mesoporous materials in periodontal regeneration. In this article, the characteristics of mesoporous materials and their application in periodontal regeneration will be reviewed.

Key words: mesoporous materials, periodontal regeneration, periodontitis