›› 2017, Vol. 37 ›› Issue (3): 271-275.

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Research progress of the roles of lncRNAs in bone development

Yu WEI,   

  • Received:2016-09-02 Revised:2016-09-23 Online:2017-03-28 Published:2017-04-12

Abstract: Long non-coding RNAs(lncRNAs) refer to the non-coding RNAs which exceed 200nt in length and lack open reading frames, and they account for a significant proportion of non-coding RNAs. LncRNAs play an important role in regulating the process of epigenetics, transcription, translation and protein modification, thus they widely participate in some important life processes including cell differentiation, individual development and so on. At the same time, more and more studies have found that lncRNAs are also closely related to the occurrence and development of some important human diseases. In this paper, the roles of lncRNAs in bone development will be reviewed.

Key words: Long non-coding RNAs(lncRNAs), bone development, bone diseases

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