›› 2017, Vol. 37 ›› Issue (3): 276-280.

• Summary • Previous Articles     Next Articles

The research development of miRNAs in bone metabolism.

  

  • Received:2016-09-26 Revised:2016-12-14 Online:2017-03-28 Published:2017-04-12

Abstract: MicroRNAs(miRNAs) was found in eukaryotes, which has the function of regulation and control of a class of endogenous non-coding RNA, and participates in a variety of important cytobiology processes. Current literature indicates that miRNAs can regulate the differentiation and bone absorption. They also regulate the ossification of cartilage. Therefore, miRNAs are powerful regulators for biological organ development and some metabolic bone diseases. In this paper, the research progress of these aspects is summarized.

Key words: microRNA;Osteoblast;osteoclast;Chondrocyte;Adipogenic;osteoporosis;osteoarthritis

CLC Number: