›› 2017, Vol. 37 ›› Issue (4): 364-368.

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Research progress on the relation between chronic periodontitis and Alzheimer disease

  

  • Received:2016-10-06 Revised:2016-11-11 Online:2017-04-28 Published:2017-04-11

Abstract: Chronic periodontitis (CP) is a kind of chronic infectious diseases caused by plaque microbial, which can destroy the periodontal tissues and is the main cause of adults tooth loss in our country. It has been a research hotspot to explore the relationship between chronic periodontitis and systemic diseases with the development of periodontal medicine. Alzheimer disease (AD) is one of the most common causes of elderly dementia neural degenerative diseases. The key pathomechanism of CP and AD is inflammatory response triggered by various inflammatory mediators. This article will review the characteristics and the mechanism of the interaction between the two diseases.

Key words: chronic periodontitis, Alzheimer disease, inflammation mediators, cognition disorders

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