›› 2017, Vol. 37 ›› Issue (4): 376-379.

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Animal model research on the effects of nasal obstruction on craniofacial and respiratory muscles in rats

  

  • Received:2016-09-05 Revised:2016-10-06 Online:2017-04-28 Published:2017-04-11
  • Contact: Min ZHU E-mail:doctorzhumin@126.com

Abstract: Respiration is a fundamental physical function for human beings. As the normal respiratory mode, nasal respiration can be changed into mouth breathing when nasal channels are obstructed. Mouth breathing can modify relevant hard and soft tissues of craniofacial structure, which finally results in craniofacial malformation. Animal models of nasal obstruction have been successfully set up on rats due to its unique advantages in the research on related mechanisms. Based on the theory of “Moss functional matrix”, condylar growth and development can be modified by surrounding micro environment, which is influenced by relevant craniofacial muscles. Postural variation of jaws induced by nasal obstruction can finally lead to craniofacial malformation via muscular mechanical transduction.

Key words: nasal obstruction, rats, craniofacial structure, muscle, respiratory muscle

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