牙源性干细胞在牙槽骨再生领域的研究进展

Abstract

Abstract: Each of the bone augmentation currently used has its own deficiencies. The bone tissue engineering provides new treatment and method for bone regeneration. It has been proved that dental stem cell possess the characteristics of osteogenic potential, easily obtained, strong proliferation ability, great differentiation potential, and weak immunogenicity. Dental stem cells have become an important source for tissue engineering.This article mainly introduces the research progress of dental stem cells in alveolar bone regeneration.

Key words: bone regeneration, dental stem cell, osteogenesis

CLC Number:

R329.2+6

References

[1]Dimitriou R, Jones E, McGonagle D, et al. Bone regeneration: current concepts and future directions[J]. BMC Med, 2011, 9:66-75.
[2]E. A. Jones, X. B. Yang. Mesenchymal stem cells and their future in bone repair[J]. Rheumatology (Oxford), 2005, 3(3):15-21.
[3]Gronthos S, Mankani M, Brahim J, et al. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo[J]. procNatl AcadSci USA, 2000, 97(25):13625-13630.
[4]Huojia Muhetaer, Muraoka N, Yoshizaki K, et al. TGF-beta3 induces ectopic mineralization in fetal Blouse dental pulp during tooth germ development[J]. Dev Growth Differ, 2005, 47(3):141—152．
[5]Amir LR, Suniarti DF, Utami S, et al. Chitosan as a potential osteogenic factor compared with dexamethasone in cultured macaque dental pulp stromal cells[J]. Cell Tissue Res, 2014, 358(2):407-415.
[6]Yang X, van der Kraan PM, Bian Z, et al. Mineralized tissue formation by BMP2-transfected pulp stem cells[J]. J Dent Res, 2009, 88(11):1020-1025.
[7]A. Morito, Y. Kida, K. Suzuki et al. Effects of basic fibroblast growth factor on the development of the stem cell properties of human dental pulp cells[J]. Arch Histol Cytol, 2009, 72(1):51–64.
[8]Kanafi MM, Ramesh A, Gupta PK, et al. Dental pulp stem cells immobilized in alginate microspheres for applications in bone tissue engineering[J]. Int Endod J, 2014, 47(7):687-697.
[9]Niu LN, Sun JQ, Li QH, et al. Intrafibrillar-silicified collagen scaffolds enhance the osteogenic capacity of human dental pulp stem cells[J]. J Dent, 2014, 42(7):839-849.
[10]Miura M, Gronthos S, Zhao M, et al. SHED: stem cells from human exfoliated deciduous teeth[J]. Proc Natl Acad Sci USA, 2003,100(10):5807-5812.
[11]Cordeiro MM, Dong Z, Kaneko T, et al. Dental pulp tissue engineering with stem cells from exfoliated deciduous teeth[J]. J Endod, 2008,34(8):962-969.
[12]Lee JY, Nam H, Park YJ, et al. The effects of plateletrich plasma derived from human umbilical cord blood on the osteogenic differentiation of human dental stem cells[J]. In Vitro Cell Dev Biol Anim, 2011, 47(2):157-164.
[13]Chadipiralla K, Yochim JM, Bahuleyan B, et al. Osteogenic differentiation of stem cells derived from human periodontal ligaments and pulp of human exfoliated deciduous teeth[J]. cell Tissue Res, 2010, 340(2):323-333.
[14]Li B, Qu C, Chen C, et al. Basic fibroblast growth factor inhibits osteogenic differentiation of stem cells from human exfoliated deciduous teeth through ERK signaling[J]. Oral Dis, 2012, 18(3):285-292.
[15]Coyac BR, Chicatun F, Hoac B, et al. Mineralization of dense collagen hydrogel scaffolds by human pulp cells[J]. J Dent Res, 2013, 92(7):648-654.
[16]De MC, Bueno DF, Martins MT, et al. Reconstruction of large cranial defects in nonimmunosuppressed experimental design with human dental pulp stem cells[J]. J Craniofac Surg, 2008, 19(1):204-210.
[17]Seo BM, Miura M, Gmnthos S, et al．Investigation of multipotent postnatal stem cells from human periodontal ligament[J]．Lancet, 2004,364(9429):149-155．
[18]Liu N, Shi S, Deng M, et al. High levels of beta-catenin signaling reduce osteogenic differentiation of stem cells in inflammatory microenvironments through inhibition of the noncanonical Wnt pathway[J]. J Bone Miner Res, 2011, 26(9):2082-2095.
[19]Lee JH, Um S, Jang JH, et al. Effects of VEGF and FGF-2 on proliferation and differentiation of human periodontal ligament stem cells[J]. cell Tissue Res, 2012, 348(3):475-484.
[20]Yu Y, Mu J, Fan Z, et al. Insulin-like growth factor 1 enhances the proliferation and osteogenic differentiation of human periodontal ligament stem cells via ERK and JNK MAPK pathways[J]. Histochem Cell Biol, 2012, 137(4):513-525.
[21]Mrozik KM, Wada N, Marino V, et al. Regeneration of periodontal tissues using allogeneic periodontal ligament stem cells in an ovine model[J]. Regen Med, 2013, 8(6), 711-723.
[22]Liu Y, Zheng Y, Ding G, et al. Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine[J]. Stem Cells, 2008, 26(4):1065-1073.
[23]Sonoyama W, Liu Y, Yamaza T, et al．Characterization of the apical papilla and its residing stem cells from human immature permanent teeth：a pilot study[J]．J Endod, 2008, 34(2):166-171．
[24]Yagyuu T, Ikeda E, Ohgushi H, et al. Hard tissue-forming potential of stem/progenitor cells in human dental follicle and dental papilla[J]. Arch Oral Biol, 2010, 55(1):68-76.
[25]Wu J, Huang GT, He W, et al. Basic fibroblast growth factor enhances stemness of human stem cells from the apical papilla[J]. J Endod, 2012, 38(5):614-622.
[26]Wang S, Mu J, Fan Z, et al. Insulin-like growth factor 1 can promote the osteogenic differentiation and osteogenesis of stem cells from apical papilla[J]. Stem Cell Res, 2012, 8(3):346-356.
[27]Wang L, Yan M, Wang Y, et al. Proliferation and osteo/odontoblastic differentiation of stem cells from dental apical papilla in mineralization-inducing medium containing additional KH(2)PO(4)[J]. Cell Prolif, 2013, 46(2):214-222.
[28]Abe S, Yamaguchi S, Watanabe A, et al. Hard tissue regeneration capacity of apical pulp derived cells (APDCs) from human tooth with immature apex[J]. Biochem Biophys Res Commun, 2008, 371(1):90-93.
[29]Morsczeck C, Gotz W, Schierholz J, et al. Isolation of precursor cells (PCs) from human dental follicle of wisdom teeth[J]. Matrix Biol, 2005, 24(2):155-165.
[30]d'Aquino R, Tirino V, Desiderio V, et al.Human neural crest-derived postnatal cells exhibit remarkable embryonic attributes either in vitro or in vivo[J].Eur Cell Mater, 2011 22(21),304-316.
[31]Handa K, Saito M, Tsunoda A, et al. Progenitor Cells From Dental Follicle Are Able to Form Cementum Matrix In Vivo[J]. Connect Tissue Res, 2009, 43(2-3):406-408.
[32]Xu LL, Liu HC, Wang DS, et al. Effects of BMP-2 and dexamethasone on osteogenic differentiation of rat dental follicle progenitor cells seeded on three-dimensional beta-TCP[J]. Biomedical materials, 2009, 4(6):065010-065018.
[33]Li C, Yang X, He Y, et al. Bone morphogenetic protein-9 induces osteogenic differentiation of rat dental follicle stem cells in P38 and ERK1/2 MAPK dependent manner[J], Int J Med Sci, 2012, 9(10):862-871.
[34]Takahashi K, Ogura N, Aonuma H et al.Bone morphogenetic protein 6 stimulates mineralization in human dental follicle cells without dexamethasone[J], Arch Oral Biol, 2013, 58(6), 690-698.
[35]Yao S, He H, Gutierrez DL, et al. Expression of bone morphogenetic protein-6 in dental follicle stem cells and its effect on osteogenic differentiation[J]. Cells Tissues Organs, 2013, 198(6):438-447.

Research progress of dental stem cells in alveolar bone regeneration

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