Abstract: [Abstract] OSAS, a conventional sleep-related breathing disorder, is characterized by repetitive upper airway obstructions and disruptive snoring during sleep, including excessive daytime sleepiness, neurocognitive dysfunction, cardiovascular disorders, metabolic dysfunction, and impaired mood and quality of life, usually along with malocclusion. Oropharyngeal airway structural segment stenosis exists in Angle Class II malocclusion. OSAS patients, especially in obese patients, apparently have craniofacial characteristics of high angle of Class Ⅱ sagittal facial type. Improving of malocclusion and modifying of pharyngeal patency by oral appliance therapy have been suggested as an alternative to various treatment modalities for OSAS. These modalities applied in treating malocclusion and OSAS can be effective. Thus, in this review, we represent several methods in treatment and therapeutic efficacy of OSAS, in addition, illustrate the morphological changes of pharyngeal airway passage and relieving symptoms of OSAS in order to provide some constructive suggestion to the future treatment of OSAS with malocclusion.

Key words: pharyngeal airway, OSAS, Class II malocclusion, modalities