Abstract: Evaluate the possible effects of menopause on the severity of periodontal disease and bone loss, for considering the therapy of periodontal disease. Methods: 50 women with chronic periodontitis, oral and periodontal parameters including: plaque index, probing depth, bleeding on probing and attachment loss were recorded. Results: The mean age of this study was 53.9±3.5 year’s old. PD, CAL, PLI, BI index and alveolar bone defect were positively correlated with the time of menopause (P<0.001) were increasing with the increase of menopause. The alveolar bone density of patients with chronic periodontitis decreased with the increase of menopause time. The alveolar bone density was negatively correlated with the time of menopause (P <0.001). Conclusions: The time of Menopause does appear to significantly influence the severity of periodontal disease and bone loss. Our results suggest that poor periodontal status may be associated with low bone mineral density of postmenopausal women.

Key words: Periodontal disease, menopause, osteoporosis