›› 2018, Vol. 38 ›› Issue (1): 83-86.

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Research progress of the promotion of nerve growth factor in implant-bone interface osseointegration

  

  • Received:2016-09-12 Revised:2016-10-16 Online:2018-01-28 Published:2018-01-31

Abstract: Nerve growth factor (NGF) is widely distributed in the central nervous system and the peripheral nervous system. Many studies have found that NGF can promote blood vessel growth, wound healing, nerve system development and bone formation. Many factors can affect the stability of implant bone, among which implant surface property is the main one. In the process of implant?osseointegration, NGF can enhance the activity of osteocyte, promote osteoblast differentiation and mineralization, and improve the formation of peripheral nerve and blood vessel; it can also effectively promote healing of bone around the implant, and thus shorten the healing time of oral implant. This paper will review the role of NGF in promoting the?implant?osseointegration.

Key words: [key words] NGF, Implant, Bone healing

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