二甲双胍潜在用途研究进展

Abstract

Abstract: Metformin is a biguanide hypoglycemic drug mainly used to treat type 2 diabetes mellitus (T2DM) and metabolic syndrome. However, the potential use of metformin goes far beyond its intended use. In recent years, with more and more studies on metformin, more effects of the drug in different situations have been discovered. In addition to the role of lowering blood sugar, metformin has the effects of anti-tumor, anti-aging, anti-inflammation, modulation of gut microbiota and potential osteogenesis. This article reviews the role of metformin in various fields and provides a reference for clinicians and researchers.

Key words: metformin, anti-tumor, anti-aging, anti-inflammatory, gut microbiota, osteogenesis

CLC Number:

R977.6

Rui ZHANG. Research progress of the potential use of metformin[J]. , 2018, 38(10): 938-941.

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