细胞膜片技术及其在种植体表面的应用进展

Abstract

Abstract: In order to improve the implant osseointegration and increase success rates of implant treatments, cell sheet technology provides a new method for surface modifications of implants from the perspective of biology. As a cell processing method capable of retaining extracellular matrix, with no scaffolds, the cell sheet can be combined with conventional implant materials to form cell sheetimplant complexes. Moreover, more and more studies have shown that the cell sheet can be used as a genetic engineering carrier to promote implant osseointegration through carrying with related osteogenic genes. However, this technique also has some problems in the application of implants, such as single fabrication method of the complexes and the unknown viability of the complexes in vivo. Therefore, this paper summarized the fabrication methods of the cell sheet and cell sheetimplant complexes, and tracking approaches of the cell sheet in vivo.

Key words: cell sheet technology, implant, surface modification

CLC Number:

R782.1

References

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Cell sheet technology and its application in surface modifications of implants

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