消退素在炎症消退中的研究进展及其在牙髓炎症调控中的应用

Abstract

Abstract: Resolution of inflammation is an actively regulated process governed by an array of endogenous mediators. Timely resolution is paramount in preventing the inflammatory over reaction. Resolvin is a recently discovered endogenous lipid regulatory mediators with proven anti-inflammatory effects. Studies have shown that resolvin can limit the excessive activation and recruitment of neutrophils, promote the clearance of apoptotic and necrotic cells, and play a protective role on the structural cells, thereby accelerating the resolution of inflammation and restoring tissue homeostasis. Topical application of resolvin, infiltration of inflammatory cells in the pulp and periapical tissue was also significantly reduced.

Key words: inflammation resolution, resolvin, dental pulp inflammation

CLC Number:

R781.3

References

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[31].

The role of resolvins in inflammation resolution and its application in the regulation of dental pulp inflammation

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