Abstract: Objective: To investigate the prevalence of developmental defect of enamel and its associated factors in the primary dentition of children aged 3 to 5 in Shanghai Pudong District, China. Methods: Clinical examination and questionnaire survey were used to make a cross-sectional survey of randomly selected 1500 children aged 3 to 5 in shanghai Pudong District, China. The questionnaire survey included the basic information and questions associated with DDE of primary teeth. Results: The prevalence of DDE in the primary teeth of children aged 3 to 5 in Shanghai Pudong District was 34.6%, including 17.3% of the whole valid samples had hypoplasia in primary dentition.Age,sex, childhood anemia and alcohol intakes during mother's pregnancy were associated to DDE of primary teeth. Conclusion: The prevalence of DDE in the primary teeth of preschoolchildren aged 3 to 5 in shanghai Pudong District was 34.6%,and the prevalence of enamel hypoplasia(EHP) in the primary teeth was 17.3%.Age, sex, childhood anemia and alcohol intakes during mother's pregnancy were associated to DDE of primary teeth.

Key words: developmental defect of enamel, enamel hypoplasia， epidemiological survey