水通道蛋白5在唾液腺分泌中的作用及其临床应用

Abstract

Abstract: Aquaporin 5 (AQP5) is a protein that can specifically transport water across membranes. It can significantly increase cell membrane water permeability, participate in water secretion and absorption, and maintain water balance inside and outside the cells. It plays a key role in human external secretion function. Recent studies have found that salivary gland secretion is inseparably related with the expression and localization of AQP5. AQP5 is clinically used as a target for the treatment of salivary gland secretion disorders, which has achieved considerable therapeutic effects. This article reviews the structure and function of AQP5 as well as its role in salivary gland secretion and clinical application.

Key words: aquaporin, AQP5, salivary gland, Sj?gren's syndrome

CLC Number:

R781.7

References 40

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The role and clinical application of AQP5 in salivary gland secretion

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