Abstract: Jaw bone defects are common in oral maxillofacial surgery, which will lead to abnormality in the function and morphology of maxillofacial region. So bone defect repair is necessary. To avoid secondary injury caused by autogenous bone harvesting, seeking an ideal bone substitute material becomes the present research focus. Dentine material has been paid much attention in recent years because of its similar characteristics to bone and merits of easy availability, simple preparation and good ability to form new bone. Researchers found that decalcification makes dentine material a more effective material which can help bone formation. This paper reviewed the characteristics, mechanism of bone formation and clinical application of decalcified dentin matrix.

Key words: decalcified dentin matrix, bone grafting, bone morphogenetic protein