纳米银颗粒用于牙周和种植体周抗菌研究进展

Abstract

Abstract: Plaque control is the central tenet of periodontal therapy. The efficacy of plaque control largely determines the prognosis of periodontitis and peri-implantitis. To enhance the effectiveness, antibiotics are usually applied adjunctively to treat severe periodontitis or prevent infection after periodontal surgery and implantation. However, antibiotics application is restricted by the induction of antibiotic resistance and their low efficiency to kill bacteria in the biofilm. Recently, due to the excellent antibacterial properties and less tendency to induce resistance, silver nanoparticles have been explored as an alternative antibacterial agent and are promising to treat periodontitis and peri-implantitis or prevent infection. Therefore, this review has focused on the advances of silver nanoparticles as potential antibacterial agents for periodontal treatment, including the antibacterial mechanism and its influential factors, cytotoxicity, the potential application in periodontitis and peri-implantitis.

Key words: periodontitis, peri-implantitis, silver nanoparticles, antibacterial, cytotoxicity

CLC Number:

R781.4

References 73

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Advances in the antibacterial therapy of periodontitis and peri-implantitis with silver nanoparticles

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