牙本质小管堵塞并诱导再矿化的研究进展

Abstract

Abstract: Dentin hypersensitivity is a temporary and sharp pain caused by external stimulation of exposed dentin, which seriously affects the quality of life of patients. A large number of studies have shown that occlusion of dentin tubules can effectively treat dentin hypersensitivity, but the therapeutic effect of simply blocking dentin tubules is not ideal. In this paper, we introduce three methods to block dentinal tubules and induce remineralization of dentinal tubules, including nano-hydroxyapatite, bioactive glass and Gallic acid / metal ion complex. These methods can not only quickly block the dentinal tubules, but also continue to play a role, so as to better plug the dentinal tubules, which can reduce the pain of patients and is expected to eventually cure dentin hypersensitivity.

Key words: dentin hypersensitivity, dentin tubule, occlusion, remineralization

CLC Number:

R781.23

Xuan-Yan ZHU Zi-Lu TIAN Hui-Min WANG Yu-bin YANG. Research progress of dentin tubule occlusion and induced remineralization[J]. , 2020, 40(9): 843-846.

References

[1] Kopycka-Kedzierawski D T, Meyerowitz C, Litaker M S, et al. Management of dentin hypersensitivity by practitioners in the national dental practice-based research network[J]. Journal Of the American Dental Association, 2017, 148(10): 728-736. [2] Zeola L F, Soares P V, Cunha-Cruz J. Prevalence of dentin hypersensitivity: Systematic review and meta-analysis[J]. Journal Of Dentistry, 2019, 81: 1-6. [3] Orchardson R, Gillam D G. Managing dentin hypersensitivity[J]. Journal Of the American Dental Association, 2006, 137(7): 990-998. [4] Katakam D, Priyadarshini S, Divakar K P, et al. An in vitro comparative evaluation of dentinal tubule occlusion by current desensitizing agents-a scanning electron microscopic study[J]. Journal Of Evolution Of Medical And Dental Sciences-Jemds, 2019, 8(4). [5] Brannstrom M. Sensitivity of dentine[J]. Oral surgery, oral medicine, and oral pathology, 1966, 21(4): 517-526. [6] Vano M, Derchi G, Barone A, et al. Reducing dentine hypersensitivity with nano-hydroxyapatite toothpaste: A double-blind randomized controlled trial[J]. Clinical Oral Investigations, 2018, 22(1): 313-320. [7] Pashley D H. How can sensitive dentine become hypersensitive and can it be reversed?[J]. Journal Of Dentistry, 2013, 41: S49-S55. [8] West N X, Seong J, Hellin N, et al. Assessment of tubule occlusion properties of an experimental stannous fluoride toothpaste: A randomised clinical in situ study[J]. Journal Of Dentistry, 2018, 76: 125-131. [9] Baglar S, Erdem U, Dogan M, et al. Dentinal tubule occluding capability of nano-hydroxyapatite; the in-vitro evaluation[J]. Microscopy Research And Technique, 2018, 81(8): 843-854. [10] Anand S, Rejula F, Sam J V G, et al. Comparative evaluation of effect of nano-hydroxyapatite and 8% arginine containing toothpastes in managing dentin hypersensitivity: Double blind randomized clinical trial[J]. Acta medica (Hradec Kralove), 2017, 60(3): 114-119. [11] Yuan P, Liu S, Lv Y, et al. Effect of a dentifrice containing different particle sizes of hydroxyapatite on dentin tubule occlusion and aqueous cr (vi) sorption[J]. International Journal Of Nanomedicine, 2019, 14: 5243-5256. [12] 杨剑珍,申晓青,刘成霞,徐平平. 不同粒径和形貌的羟基磷灰石对牙本质小管的堵塞作用及耐磨性研究[J]. 口腔疾病防治, 2017, 25(05): 288-293. [13] Krishnan V, Bhatia A, Varma H. Development, characterization and comparison of two strontium doped nano hydroxyapatite molecules for enamel repair/regeneration[J]. Dental Materials, 2016, 32(5): 646-659. [14] Bae J, Son W-S, Yoo K-H, et al. Effects of poly(amidoamine) dendrimer-coated mesoporous bioactive glass nanoparticles on dentin remineralization[J]. Nanomaterials, 2019, 9(4). [15] Liang K, Yuan H, Li J, et al. Remineralization of demineralized dentin induced by amine-terminated pamam dendrimer[J]. Macromolecular Materials and Engineering, 2015, 300(1): 107-117. [16] Lin X, Xie F, Ma X, et al. Fabrication and characterization of dendrimer-functionalized nano-hydroxyapatite and its application in dentin tubule occlusion[J]. Journal Of Biomaterials Science-Polymer Edition, 2017, 28(9): 846-863. [17] Jung J-H, Park S-B, Yoo K-H, et al. Effect of different sizes of bioactive glass-coated mesoporous silica nanoparticles on dentinal tubule occlusion and mineralization[J]. Clinical Oral Investigations, 2019, 23(5): 2129-2141. [18] Yu J, Yang H, Li K, et al. A novel application of nanohydroxyapatite/mesoporous silica biocomposite on treating dentin hypersensitivity: An in vitro study[J]. Journal Of Dentistry, 2016, 50: 21-29. [19] Wang R, Wang Q, Wang X, et al. Enhancement of nano-hydroxyapatite bonding to dentin through a collagen/calcium dual-affinitive peptide for dentinal tubule occlusion[J]. Journal Of Biomaterials Applications, 2014, 29(2): 268-277. [20] Ma Q, Wang T, Meng Q, et al. Comparison of in vitro dentinal tubule occluding efficacy of two different methods using a nano-scaled bioactive glass-containing desensitising agent[J]. Journal Of Dentistry, 2017, 60: 63-69. [21] Jung J-H, Kim D-H, Yoo K-H, et al. Dentin sealing and antibacterial effects of silver-doped bioactive glass/mesoporous silica nanocomposite: An in vitro study[J]. Clinical Oral Investigations, 2019, 23(1): 253-266. [22] Lin W-T, Chen J-C, Hsiao Y-C, et al. Re-crystallization of silica-based calcium phosphate glass prepared by sol-gel technique[J]. Ceramics International, 2017, 43(16): 13388-13393. [23] Wong K-W, Chien C-S, Hsiao Y-C, et al. Re-crystallization of bioactive glass mixed with various hardening agents[J]. Ceramics International, 2017, 43(9): 7026-7032. [24] Chen W-C, Chen C-H, Kung J-C, et al. Phosphorus effects of mesoporous bioactive glass on occlude exposed dentin[J]. Materials, 2013, 6(11): 5335-5351. [25] Prajatelistia E, Ju S-W, Sanandiya N D, et al. Tunicate-inspired gallic acid/metal ion complex for instant and efficient treatment of dentin hypersensitivity[J]. Advanced Healthcare Materials, 2016, 5(8): 919-927. [26] Kimura Y, Wilder-Smith P, Yonaga K, et al. Treatment of dentine hypersensitivity by lasers: A review[J]. Journal Of Clinical Periodontology, 2000, 27(10): 715-721. [27] Bal M V, Keskiner I, Sezer U, et al. Comparison of low level laser and arginine-calcium carbonate alone or combination in the treatment of dentin hypersensitivity: A randomized split-mouth clinical study[J]. Photomedicine and Laser Surgery, 2015, 33(4): 200-205. [28] Berkathullah M, Farook M S, Mahmoud O. The effectiveness of remineralizing agents on dentinal permeability[J]. Biomed Research International, 2018 [29] Cao Y, Liu W, Ning T, et al. A novel oligopeptide simulating dentine matrix protein 1 for biomimetic mineralization of dentine[J]. Clinical Oral Investigations, 2014, 18(3): 873-881. [30] Liang K, Xiao S, Liu H, et al. 8dss peptide induced effective dentinal tubule occlusion in vitro[J]. Dental Materials, 2018, 34(4): 629-640.

Research progress of dentin tubule occlusion and induced remineralization

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