›› 2020, Vol. 40 ›› Issue (9): 851-854.

• Summary • Previous Articles     Next Articles

Expression of Runx2 gene and periodontal rebuilt in orthodontic tooth movement

  

  • Received:2019-12-17 Revised:2020-01-26 Online:2020-09-28 Published:2020-10-07

Abstract: Runx2 is a specific transcription factor of osteogenic differentiation, which plays an important role in the formation and differentiation of osteoblasts, the formation and activation of osteoclasts. Orthodontic tooth movement(OTM) is a process in which teeth compress or stretch the periodontal ligament after being subjected to a certain orthodontic force, and the periodontal tissue is rebuilt within the physiological limit, and then the tooth movement is achieved.Many scholars are interested in the methods of accelerating orthodontic tooth movement and maintaining orthodontic tooth movement. It is considered that Runx2 plays an important role in periodontal remodeling during orthodontic tooth movement, and its gene expression plays a positive role in orthodontic tooth movement periodontal remodeling. In this paper, the related research results are described.

Key words: Runx2, tooth movement, orthodontic force, osteoblasts

CLC Number: