西格列汀潜在用途研究进展

Abstract

Abstract: Sitagliptin is a highly selective dipeptidyl peptidase-4(DPP-4) inhibitor. As the first drug of its kind approved for the treatment of type 2 diabetes, it has the advantages of good efficacy, tolerance, and a low occurrence rate of hypoglycemia and weight gain. In recent years, with more and more studies on sitagliptin conducted, more effects of the drug in different situations have been discovered. In addition to the role of lowering blood sugar, sitagliptin also has the effects of anti-inflammation, anti-tumor, potential renal protection, cardiovascular protection, and tissue regeneration. This article reviews the roles of sitagliptin in various fields, which will provide a reference for the diagnosis and treatment of related diseases and tissue regeneration.

Key words: sitagliptin, anti-inflammation, anti-tumor, renal protection, cardiovascular protection, tissue regeneration

CLC Number:

R780.1

Xiang LIU. Research progress of the potential use of sitagliptin[J]. , 2021, 41(1): 76-82.

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