›› 2021, Vol. 41 ›› Issue (3): 259-264.

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Research progress of melatonin in the diagnosis and treatment of periodontitis

  

  • Received:2020-07-27 Revised:2020-09-20 Online:2021-03-28 Published:2021-03-28

Abstract: Melatonin is a tryptophan-derived hormone secreted by the pineal gland of the brain. In recent years,a large number of studies have found that melatonin can promote periodontal health,so its role in periodontitis has received more and more attention. This article reviews the correlation between melatonin concentration in saliva and periodontitis,the mechanisms of melatonin affecting periodontitis,and the progress in the application of melatonin as an exogenous chemical factor in periodontal bone tissue engineering, in hopes of providing new ideas for the diagnosis and treatment of periodontitis.

Key words: melatonin, bone, periodontitis, tissue engineering