MicroRNA与舌鳞状细胞癌相关性的研究进展

Abstract

Abstract: Tongue Squamous Cell Carcinoma is the most aggressive type of oral malignancy, accounting for 50 to 60 percent of oral cancers. Despite the advances in diagnostic and therapeutic techniques, TSCC remains one of the deadliest forms of head and neck cancer. MicroRNAs are small, endogenous, non-coding RNAs that are responsible for post-transcriptional regulation of mRNA expression. As effective oncogenes or tumor suppressors, they participate in the regulation of the pathogenesis and process of various diseases including TSCC. A large number of MicroRNA analyses were performed in TSCC samples, revealing their effects on the potential molecular mechanisms of TSCC initiation, development, metastasis, chemotherapy resistance, recurrence, and prognosis. This paper summarizes the correlation between MicroRNA and TSCC.

Key words: MicroRNA, Tongue Squamous Cell Carcinoma, prognosis

CLC Number:

R782.05

References

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Progress of research on the correlation between MicroRNA and the tongue squamous cell carcinoma

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