Abstract: Dysbiotic periodontal microbiota is closely associated with periodontal diseases and many systemic diseases. Here we briefly summarize the roles of periodontitis and dysbiotic periodontal microbiota in cardiocerebrovascular diseases including hypertension, atherosclerosis, myocardial infarction, cardiac hypertrophy, heart failure and stroke. Correlations between periodontitis and these cardiocerebrovascular diseases have been established in recent years. There are a few data supporting causal relationships between periodontitis and some cardiocerebrovascular diseases such as hypertension and atherosclerosis, but more evidence is warranted. Furthermore, causal relationships between periodontitis and other cardiocerebrovascular diseases are yet to be established. The importance of dysbiotic periodontal microbiota in cardiocerebrovascular diseases except stroke has been supported by some data. However, research in more depth is required to fully comprehend the critical function and mechanism of dysbiotic periodontal microbiota in these diseases. Results of these studies will provide more evidence and ideas for joint prevention and control of oral diseases and cardiocerebrovascular diseases.

Key words: periodontal microbiota, periodontitis, cardio-cerebrovascular disease