Abstract: Objective　 To investigate the clinical application of multimodal mixed reality technology in the treatment of craniofacial, head and neck tumor, thus providing a reference for the treatment of tumor, enhancing the treatment efficiency of the disease, and improving the prognosis of patients. Methods Forty-six cases of craniofacial head and neck tumor treated in our hospital were analyzed retrospectively, who were divided into two groups. The patients in the control group accepted the examination of magnetic resonance imaging, computed tomography, and then they underwent surgery based on these traditional two-dimensional imaging data. Patients in the observation group used Mimics software for data processing and fusion, and the three-dimensional model was constructed by mixed reality (MR) technology, which assisted preoperative analysis and intraoperative guidance. The communication time, satisfaction, and anxiety of the patients in each group before operation were collected. The operation time, amount of bleeding during operation, postoperative complications and recovery were recorded. Results Compared with the control group, there was less preoperative communication time, higher level of satisfaction, less anxiety, shorter operation duration, and less intraoperative blood loss in the observation group. The differences were statistically significant (P<0.05). In addition, 11 patients in the control group had postoperative complications, while only 4 patients in the observation group occurred. As for rehabilitation, there were obvious differences in language communication ability, activity of daily living and prognostic scores between two groups (P<0.05). All rehabilitation scores in the observation group were better than the control group. Conclusion The status of craniofacial head, and neck tumors can be fully demonstrated by multimodal MR imaging technology, which helps to reduce the time of preoperative communication and relieve anxiety, reduce the occurrence of postoperative complications, improve patient prognosis and promote patient recovery. The new technology can be further promoted in clinic.

Key words: Multimodal mixed reality technology, Head and neck tumors, Prognosis, Rehabilitation