›› 2021, Vol. 41 ›› Issue (9): 834-838.

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Effects of Bacteriophage on the Development and Treatment of Oral Diseases and Its Mechanism

  

  • Received:2021-01-14 Revised:2021-03-07 Online:2021-09-28 Published:2021-09-23
  • Supported by:
    Researches on the Pathogenesis and New Preventive Technologies of Early Childhood Caries;Dental Treatment and Oral Health Management for Children and Adolescents

Abstract: Bacteriophage is a kind of virus that specifically infects microorganisms such as bacteria and fungi, and is a specific and important part of the oral ecosystem. A variety of phages are evenly distributed in the oral microbial community, dental plaque and pharyngeal isthmus community. Their interaction with the bacterial community maintains the stability of the oral micro-ecological system. Previous studies have shown that phages relate to the development of oral diseases and play an important role in the treatment of related oral diseases. This article reviews the distribution characteristics of bacteriophage in oral microbial communities, as well as its role and mechanism in the occurrence, development and treatment of oral diseases, aiming to provide some new ideas for the pathogenesis and clinical treatment of related oral diseases.

Key words: Bacteriophage, Oral micro-ecology, Oral disease, Phage therapy

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