Abstract: Objective The study aimed to improve quality control of dental instruments Methods Here were 1458 dental instruments in our department (From Jan.2010 Jun.2011). 594 dental instruments were used from Jan 2010 to Jun 2010 and they were in the study group. Whereas the others used from Jul 2010 to Jul 2011 were served as study group. We compared the rates of the effective acceptance, the rates of instrument loss, and the rates of destination clearance of dental instruments after the administration of PDCA circulation. Results The effective acceptance rates were 59.9% and 100% in the control and study groups, destination clear rates 85.90% and 99.80%, and loss rates 3.87% and 0.21%, respectively. Statistically significant differences were observed between groups. Conclusion PDCA circulation was used in the management of dental instruments. It improved the quality of dental instruments significantly. It also reduced the rate of hospital infection. Besides, it reduced the medical expenditure of oral departments .