Abstract: Abstract: Instrument separation mainly refers to the endodontic instruments fractured in root canal or beyond the apex by accident in the process of root canal treatment. Such an error prevents the achievement of efficient cleaning and shaping, which in turn possibly results in the failure of the treatment. The aim of the following review was to analyze the literature assessing the endodontic instrument fracture, focusing on its incidence, prevention and treatment.

Key words: instrument separation, nickel-titanium instruments, root canal preparation