›› 2015, Vol. 35 ›› Issue (9): 786-788.

• Summary • Previous Articles     Next Articles

The effects of inflammatory microenvironment on regeneration of periodontal tissue

  

  • Received:2015-03-09 Revised:2015-04-30 Online:2015-09-28 Published:2015-09-14

Abstract: Chronic periodontitis is a kind of chronic inflammatory disease characterized by periodontal tissue damage.The ultimate therapeutic aim of periodontal disease is to obtain periodontal tissue regeneration.The local inflammatory microenvironment caused by periodontal disease not only leads to periodontal tissue damage,but also affects the process of periodontal regeneration.For example,it can affect the proliferation and differentiation of periodontal ligament stem cells and stifle the function of growth factors.This review discussed the effects of the inflammatory microenvironment on the regeneration of periodontal tissue.

Key words: inflammatory microenvironment, periodontal regeneration, enamel matrix protein, periodontal ligament stem cells, bone marrow mesenchymal stem cells

CLC Number: