›› 2018, Vol. 38 ›› Issue (11): 1031-1034.
• 综述 • 上一篇 下一篇
郭超1,陈晓涛2
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摘要: [摘要]Th17 细胞在炎症状态下特征性分泌白细胞介素-17(IL-17),在不同机体环境下表现不同生物学特征。IL-17协同多种细胞因子通过上调Fas/FasL,参与细胞凋亡。本文就IL-17细胞因子与破骨细胞凋亡相关关系的研究进展进行综述。
关键词: 破骨细胞, 白细胞介素-17, 细胞凋亡, Fas/FasL
Abstract: IL-17 is the cytokine secreted by the subgroup of CD4+ T cells named T helper 17, which plays different biological characteristics in different organic environments. It suggests that IL-17 plays an important role in the apoptosis of osteoclasts. The up-regulation of Fas/Fas with the assistance of IL-17 and various cytokines may take part in apoptosis. This paper reviewed the research progress of IL-17 and its relationship with osteoclasts apoptosis.
Key words: Osteoclasts, IL-17, apoptosis, Fas/FasL
中图分类号:
R780.2
郭超 陈晓涛. 白细胞介素-17在破骨细胞凋亡中的作用研究进展[J]. , 2018, 38(11): 1031-1034.
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