›› 2017, Vol. 37 ›› Issue (10): 932-936.

• 综述 • 上一篇    下一篇

脂肪因子对牙周炎症组织影响机制的研究

胥丹妮,林晓萍   

  1. 中国医科大学附属盛京医院
  • 收稿日期:2017-02-24 修回日期:2017-04-10 出版日期:2017-10-28 发布日期:2017-10-13
  • 通讯作者: 胥丹妮 E-mail:372960978@qq.com
  • 基金资助:
    国家自然科学基金;中华口腔医学会专项基金研究项目

The research of mechanism in adipokines on periodontal inflammatory tissue

  • Received:2017-02-24 Revised:2017-04-10 Online:2017-10-28 Published:2017-10-13

摘要: 肥胖作为全球范围内的流行病,与某些系统性疾病如糖尿病、高血压、心血管疾病等密切相关,并与牙周炎具有相关性,二者之间能够相互影响。脂肪组织能分泌一系列的脂肪因子,如内脂素、瘦素、抵抗素、脂联素等,同时这些脂肪因子也存在于牙周组织细胞中。脂肪因子不仅能调节胰岛素的敏感性同时也参与机体的炎症反应,故两种疾病的相关性可能通过脂肪因子联系起来。本文就脂肪因子对牙周炎的影响作一简要综述。

关键词: 肥胖, 脂肪因子, 牙周炎

Abstract: As a global epidemic, obesity is higly correlated with certain systemic diseases such as diabetes, hypertension, cardiovascular disease, etc., and particularly has a close correlation with periodontitis. Adipose tissue can secrete a series of adipocytokines, such as visfatin, leptin, resistin, adiponectin, etc., and it also exists in the cells of periodontal tissue. Adipokines can not only regulate the sensitivity of insulin but also participate in body's inflammatory response, therefore, these two diseases may be linked by adipokines. This review focuses on the effects of adipokines on periodontitis.

Key words: obesity, adipocytokines, periodontitis

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