›› 2020, Vol. 40 ›› Issue (11): 1054-1060.
• 综述 • 上一篇
周健1,涂业颖1,赵子慕2,黄必行1,金佳杨1,林海燕1
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摘要： 骨形态发生蛋白异源二聚体较同源二聚体具有更低的使用剂量和更高的诱导成骨能力，因而受到广泛关注。本文介绍了BMP异源二聚体的相关研究，包括种类结构、作用机制和在诱导成骨方面的研究，比较其与BMP同源二聚体的功能差异，并对其前景作出展望。
关键词: 骨形态发生蛋白, 异源二聚体, 同源二聚体, 诱导成骨
Abstract: Bone morphogenetic protein heterodimers have received much attention because they have lower dosages and higher osteogenesis-inducing ability than homodimers. This article introduces the related research of BMP heterodimers, including species and structure, mechanism of action, and research on osteoinduction, to compare the functional differences between them and BMP homodimers, and prospect their future.
Key words: bone morphogenetic protein, heterodimer, homodimer, osteoinduction
中图分类号:
R780.2
周健 涂业颖 赵子慕 黄必行 金佳杨 林海燕. 骨形态发生蛋白异源二聚体诱导成骨的研究新进展[J]. 口腔医学, 2020, 40(11): 1054-1060.
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