肾透明细胞癌腮腺转移1例及文献复习

doi:10.13591/j.cnki.kqyx.2023.11.011

摘要/Abstract

摘要：

肾透明细胞癌是泌尿系统的常见肿瘤,具有高转移潜能,常通过肾静脉和下腔静脉进行血行播散,最常见的转移部位是肺、骨和肝。转移至腮腺的肾透明细胞癌罕见。现报道1例转移至腮腺的肾透明细胞癌,并结合相关文献对其进行讨论,为临床同类疑难病例的诊治提供经验和参考。

关键词: 腮腺, 肾透明细胞癌, 转移

Abstract:

Renal clear cell carcinoma is a common tumor of the urinary system with high metastatic potential. It often hematogenously spreads through the renal vein and inferior vena cava, and the most common sites of metastasis are lung, bone, and liver. Clear cell carcinoma of the kidney that metastasizes to the parotid gland is rare. One case of renal clear cell carcinoma metastasized to the parotid gland is reported and discussed in combination with relevant literature, which provides experience and reference for the diagnosis and treatment of similar difficult clinical cases.

Key words: parotid, renal clear cell carcinoma, metastasis

中图分类号:

白雪颖, 沙桐, 史册. 肾透明细胞癌腮腺转移1例及文献复习[J]. 口腔医学, 2023, 43(11): 1024-1027.

BAI Xueying, SHA Tong, SHI Ce. Renal clear cell carcinoma with parotid metastasis: A case report and literature review[J]. Stomatology, 2023, 43(11): 1024-1027.

图/表 2

参考文献 31

[1]	Ljungberg B, Albiges L, Abu-Ghanem Y, et al. European Association of Urology Guidelines on Renal Cell Carcinoma:The 2022 Update[J]. Eur Urol, 2022, 82(4):399-410. doi: 10.1016/j.eururo.2022.03.006 pmid: 35346519
[2]	Spyropoulou D, Tsiganos P, Dimitrakopoulos FI, et al. Radiotherapy and renal cell carcinoma:A continuing saga[J]. In Vivo, 2021, 35(3):1365-1377. doi: 10.21873/invivo.12389 pmid: 33910814
[3]	Santana T, Custódio M, DaylaMelo Oliveira C, et al. Parotid metastasis of clear cell renal cell carcinoma 8 years after nephrectomy[J]. Oral Oncol, 2021, 122:105561. doi: 10.1016/j.oraloncology.2021.105561
[4]	Gopan G, Kamala LH, Radhakrishnan N. Renal cell carcinoma presenting as bulky parotid massacase report and review of literature[J]. Indian J Surg Oncol, 2021, 12(2):378-382.
[5]	Lieder A, Guenzel T, Lebentrau S, et al. Diagnostic relevance of metastatic renal cell carcinoma in the head and neck:An evaluation of 22 cases in 671 patients[J]. Int Braz J Urol, 2017, 43(2):202-208. doi: 10.1590/S1677-5538.IBJU.2015.0665 pmid: 27649110
[6]	Ading H, Huimin L, Huasheng L, et al. Metastatic parotid gland malignancy:A preliminary study in an eastern Chinese population[J]. J Stomatol Oral Maxillofac Surg, 2023, 124(2):101309. doi: 10.1016/j.jormas.2022.10.008
[7]	Franzen AM, Günzel T, Lieder A. Parotid gland metastases of distant primary tumours:A diagnostic challenge[J]. Auris Nasus Larynx, 2016, 43(2):187-191. doi: 10.1016/j.anl.2015.09.010 pmid: 26526643
[8]	Danić P, Danić D, Macan D. Tongue metastasis as an initial presentation of renal cell carcinoma[J]. Med Glas (Zenica),2018,15(1):52-58.
[9]	Nisi M, Izzetti R, Graziani F, et al. Renal cell carcinoma metastases to the oral cavity:Report of 2 cases and review of literature[J]. J Oral Maxillofac Surg, 2020, 78(9):1557-1571. doi: 10.1016/j.joms.2020.04.001
[10]	Majewska H, Skálová A, Radecka K, et al. Renal clear cell carcinoma metastasis to salivary glands a series of 9 cases:Clinico-pathological study[J]. Pol J Pathol, 2016, 67(1):39-45. pmid: 27179273
[11]	Morita Y, Kashima K, Suzuki M, et al. Differential diagnosis between oral metastasis of renal cell carcinoma and salivary gland cancer[J]. Diagnostics (Basel), 2021, 11(3):506.
[12]	Kar A, Pattnaik K, Kar T, et al. Clear cell lesions in pathology:Histomorphologic approach to diagnosis[J]. Indian J Pathol Microbiol, 2020, 63(2):177-187. doi: 10.4103/IJPM.IJPM_791_19
[13]	Schmitz JP, Hollinger JO. The critical size defect as an experimental model for craniomandibulofacial nonunions[J]. Clin Orthop Relat Res, 1986(205):299-308.
[14]	Tajima S, Namiki I, Koda K. A clear cell variant of mucoepidermoid carcinoma harboring CRTC1-MAML2 fusion gene found in buccal mucosa:Report of a case showing a large clear cell component and lacking typical epidermoid cells and intermediate cells[J]. Med Mol Morphol, 2017, 50(2):117-121. doi: 10.1007/s00795-015-0120-5 pmid: 26297211
[15]	Gomes PS, Fernandes MH. Rodent models in bone-related research:The relevance of calvarial defects in the assessment of bone regeneration strategies[J]. Lab Anim, 2011, 45(1):14-24.
[16]	Zirong C, Ni W, Jian-Liang L, et al. The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma[J]. JCI Insight, 2021, 6(7):e139497.
[17]	Daoud EV, McLean-Holden AC, Pfeifer CM, et al. Pediatric warthin-like mucoepidermoid carcinoma:Report of two cases with one persistent/recurrent as conventional mucoepidermoid carcinoma[J]. Head Neck Pathol, 2020, 14(4):923-928. doi: 10.1007/s12105-020-01156-w
[18]	Sakamoto S, Miyauchi M, Ando T, et al. Non-sebaceous lymphadenoma-like mucoepidermoid carcinoma:A case report[J]. Pathol Int, 2022, 72(7):371-375. doi: 10.1111/pin.v72.7
[19]	Peiffer BJ, Qi L, Ahmadi AR, et al. Activation of BMP signaling by FKBP12 ligands synergizes with inhibition of CXCR4 to accelerate wound healing[J]. Cell Chem Biol, 2019, 26(5):652-661. doi: S2451-9456(19)30033-9 pmid: 30827938
[20]	Haller F, Bieg M, Will R, et al. Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands[J]. Nat Commun, 2019, 10(1):368. doi: 10.1038/s41467-018-08069-x pmid: 30664630
[21]	Viswanathan K, Beg S, He B, et al. NR4A3 immunostainis a highly sensitive and specific marker for aciniccell carcinoma in cytologic and surgical specimens[J]. Am J Clin Pathol, 2022, 157(1):98-108. doi: 10.1093/ajcp/aqab099
[22]	Katsuno-Kambe H, Teo JL, Ju RJ, et al. Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation[J]. eLife, 2021, 10:e67915.
[23]	Corps K, Stanwick M, Rectenwald J, et al. Skeletal deformities in osterix-Cre; Tgfbr2^f/fmice may cause postnatal death[J]. Genes, 2021, 12(7):975. doi: 10.3390/genes12070975
[24]	McHugh JB, Hoschar AP, Dvorakova M, et al. p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinoma[J]. Head Neck Pathol, 2007, 1(2):123-131. doi: 10.1007/s12105-007-0031-4 pmid: 20614263
[25]	Gubbiotti MA, Montone K, Zhang P, et al. A contemporary update on hyalinizing clear cell carcinoma:Compilation of all in-house cases at our institution and a literature review spanning 2015—2020[J]. Hum Pathol, 2021, 111:45-51. doi: 10.1016/j.humpath.2021.01.007 pmid: 33577927
[26]	Franzen AM, Glitzky S, Moganti A, et al. Metastases to both parotid glands six and twelve years after resection of renal cell carcinoma[J]. Case Rep Med, 2018, 2018:7301727.
[27]	Yatabe Y, Dacic S, Borczuk AC, et al. Best practices recommendations for diagnostic immunohistochemistry in lung cancer[J]. J Thorac Oncol, 2019, 14(3):377-407. doi: S1556-0864(18)33514-7 pmid: 30572031
[28]	Du T, Pan L, Chengyou Z, et al. Matrix Gla protein (MGP), GATA3, and TRPS1:A novel diagnostic panel to determine breast origin[J]. Breast Cancer Res, 2022, 24(1):70. doi: 10.1186/s13058-022-01569-1
[29]	Wu CE, Tzen CY, Wang SY, et al. Clinical diagnosis of gastrointestinal stromal tumor (GIST):From the molecular genetic point of view[J]. Cancers, 2019, 11(5):679. doi: 10.3390/cancers11050679
[30]	Danfeng L, Lesang S, Meng L, et al. Circulating tumor cells:Biology and clinical significance[J]. Signal Transduct Target Ther, 2021, 6(1):404.
[31]	Khalil BD, Sanchez R, Rahman T, et al. An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy[J]. J Exp Med, 2022, 219(1):e20210836.