口腔医学 ›› 2024, Vol. 44 ›› Issue (2): 152-155.doi: 10.13591/j.cnki.kqyx.2024.02.014

• 综述 • 上一篇    下一篇

牙龈卟啉单胞菌在非酒精性脂肪肝病进展中的作用

戴柯,戴周丽,刘荣场,查光玉,曹明国()   

  1. 丽水学院医学院,浙江丽水(323000)
  • 收稿日期:2022-08-17 出版日期:2024-02-28 发布日期:2024-02-04
  • 通讯作者: 曹明国 E-mail: cmg@lsu.edu.cn
  • 基金资助:
    丽水市科技局自筹类公益性技术应用研究项目(2022SJZC005)

The role of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease

DAI Ke,DAI Zhouli,LIU Rongchang,ZHA Guangyu,CAO Mingguo()   

  1. College of Medicine, Lishui University, Lishui 323000, China
  • Received:2022-08-17 Online:2024-02-28 Published:2024-02-04

摘要:

以牙龈卟啉单胞菌为代表的牙周致病菌不仅危害口腔健康,还与非酒精性脂肪肝病等口腔外疾病有着重要联系。牙龈卟啉单胞菌及其产物可通过血行途径和肠道途径等多种途径促进非酒精性脂肪肝病的发展,本文就相关作用途径及可能机制作一综述。

关键词: 牙龈卟啉单胞菌, 牙周炎, 非酒精性脂肪肝病, 血行途径, 肠道途径

Abstract:

Porphyromonas gingivalis(P. gingivalis), a key pathogen of periodontitis, not only harms oral health, but also has an important relationship with the development of many extraoral diseases, such as non-alcoholic fatty liver disease. P. gingivalis and its products can promote the development of non-alcoholic fatty liver disease through hematogenous and intestinal pathways. In this paper, the pathway and possible internal mechanisms involved are briefly described.

Key words: Porphyromonas gingivalis, periodontitis, non-alcoholic fatty liver disease, hematogenous pathway, intestinal pathway

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