LIM矿化蛋白1在牙髓干细胞和骨髓间充质干细胞中的研究进展

Abstract

Abstract: The LIM mineralization protein1 (LMP1) is a kind of intracellular signal transduction molecule which plays an important role in facilitating bone formation during the process of osteoblast differentiation according to both in vivo and in vitro studies. So far, it has been believed that LMP1 functions by stimulating the synthesis and secretion of certain factors like bone morphogenetic protein (BMP) which can induce bone formation, thus improving the osteogenic activity of BMP and other osteogenic factors. This article reviewed the role of LMP1 and the research progress concerning the mineralization of dental pulp stem cells (DPSC) and bone marrow stromal cells (BMSC).

Key words: LIM mineralization protein1, BMP, DPSC, BMSC

CLC Number:

R780.2

References

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Research progress of the role of LIM mineralization protein1 in dental pulp stem cells and bone marrow mesenchymal stem cells

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