富血小板纤维蛋白辅助治疗牙龈退缩的临床效果及患者满意度评价

Abstract

Abstract: Objective To evaluate and compare the clinical effects and patients′ satisfaction with treatment of Miller Ⅰ or Ⅱ gingival recession by coronally advanced flap alone or with platelet rich fibrin(PRF). Methods Thirty patients with Miller Ⅰ or Ⅱ gingival recession and willing to undergo surgical treatment were selected and divided into experimental group (coronally advanced flap combined with PRF) and control group (coronally advanced flap). Periodontal probing depth, keratinized gingiva width, gingival recession depth and root coverage were recorded before surgery, 3 months and 6 months after surgery. The clinical efficacy of the two groups was analyzed, and the satisfaction questionnaire was filled out and analyzed. Results The clinical indexes of gingival recession depth and keratinized gingiva width at 3 and 6 months after surgery were significantly improved compared with those before operation in the experimental group and the control group, and the differences were statistically significant (P<0.05). The width of keratinized gingiva between the two groups was statistically different at 3 and 6 months after surgery (P<0.05). There were no statistically significant differences in the periodontal probing depth, gingival recession depth, and root coverage between the two groups at 3 months and 6 months after surgery (P>0.05). There was no significant difference in the periodontal probing depth between the two groups at 3 months and 6 months after surgery compared with that before the operation (P>0.05). The satisfaction of patients in the experimental group was significantly higher than that in the control group, and the difference was statistically significant (P<0.05). Conclusion The results of this study further confirm that these two methods are effective for the treatment of Miller Ⅰand Ⅱ gingival recession, and the adjuvant application of PRF can increase the width of postoperative keratinized gingiva and improve patients′ satisfaction.

Key words: coronally advanced flap, platelet rich fibrin, gingival recession, patients’ satisfaction

CLC Number:

R781.44

References 20

[1]	Miller PD.A classification of marginal tissue recession[J].Int J Periodontics Restorative Dent,1985,5(2):8-13.
[2]	孟焕新.临床牙周病学[M].2版.北京:北京大学医学出版社,2014:228-231.
[3]	Tonetti MS,Jepsen S,Working Group 2 of the European Workshop on Periodontology.Clinical efficacy of periodontal plastic surgery procedures:consensus report of Group 2 of the 10th European Workshop on Periodontology[J].J Clin Periodontol ,2014, 41(Suppl 15):S36–S43.
[4]	Chambrone L,Pannuti CM,Tu YK,et al.Evidence-based periodontal plastic surgery. II. An individual data meta-analysis for evaluating factors in achieving complete root coverage[J].J Periodontol,2012,83(4):477-490.
[5]	Sanz M,Simion M.Surgical techniques on periodontal plastic surgery and soft tissue regeneration: consensus report of group 3 of the 10th European workshop on periodontology[J].J Clin Periodontol,2014,41(Suppl15):92-97.
[6]	Griffin TJ,Cheung WS,Zavras AI,et al.Postoperative complications following gingival augmentation procedures[J].J Periodontol,2006,77(12):2070-2079.
[7]	Cortellini P,Tonetti M,Baldi C,et al.Does placement of a connective tissue graft improve the outcomes of coronally advanced flap for coverage of single gingival recessions in upper anterior teeth?A multi-centre,randomized,double-blind,clinical trial[J].J Clin Periodontol,2009,36(1):68-79.
[8]	Cairo F,Nieri M,Pagliaro U.Efficacy of periodontal plastic surgery procedures in the treatment of localized facial gingival recessions.A systematic review[J].J Clin Periodontol, 2014,41(Suppl 15): S44–S62.
[9]	Cairo F,Pagliaro U,Nieri M.Treatment of gingival recession with coronally advanced flap procedures:a systematic review[J].J Clin Periodontol,2008,35(8): 136-162.
[10]	Chambrone L,Tatakis DN.Periodontal soft tissue root coverage procedures:a systematic review from the AAP Regeneration Workshop[J].J Periodontol,2015, 86(Suppl 2):S8–S51.
[11]	Pini Prato G,Rotundo R,Cairo F,et al.Long-term 8-year outcomes of coronally advanced flap for root coverage[J].J Periodontol, 2012,83(5):590-4.
[12]	Dohan DM,Choukroun J,Diss A,et al.Platelet-rich fibrin (PRF):A second- generation platelet concentrate.Part I:Technological concepts and evolution[J].Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2006,101(3):e37-e44．
[13]	Dohan DM, Choukroun J,Diss A,et al.Platelet-rich fibrin (PRF):A second- generation platelet concentrate.Part II:Platelet-related biologic features[J].Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2006,101(3):e45-e50．
[14]	Dohan DM,Choukroun J,Diss A,et al.Platelet-rich fibrin (PRF):A second- generation platelet concentrate.Part III:Leucocyte activation:A new feature for platelet concentrates? [J].Oral Surg Oral Med Oral Pathol Oral Radiol Endod,2006,101(3):e51-e55．
[15]	Castro AB, Meschi N,Temmerman A,et al.Regenerative potential of leucocyte- and platelet-rich fibrin.Part A:intra-bony defects,furcation defects and periodontal plastic surgery.A systematic review and meta-analysis[J].Journal of Clinical Periodontology, 2017,44(1):67-82.
[16]	Zhou S,Sun C,Huang S,et al.Efficacy of adjunctive bioactive materials in the treatment of periodontal intrabony defects:a systematic review and meta-analysis[J].Biomed Res Int,2018,8670832.
[17]	Dohan Ehrenfest DM,Del Corso M,Diss A,et al.Three-dimensional architecture and cell composition of a Choukroun’s platelet-rich fibrin clot and membrane[J].J Periodontol,2010,81(4):546-555.
[18]	Padma R,Shilpa A,Kumar PA,et al.A split mouth randomized controlled study to evaluate the adjunctive effect of platelet-rich fibrin to coronally advanced flap in miller's class-I and II recession defects[J].J Indian Soc Periodontol,2013,17(5):631-636.
[19]	Thamaraiselvan M,Elavarasu S,Thangakumaran S,et al.Comparative clinical evaluation of coronally advanced flap with or without platelet-rich fibrin membrane in the treatment of isolated gingival recession[J].J Indian Soc Periodontol,2015,19(1):66-71.
[20]	Potey AM,Kolte RA,Kolte AP,et al.Coronally advanced flap with and without platelet-rich fibrin in the treatment of multiple adjacent recession defects: A randomized controlled split-mouth trial[J].J Indian Soc Periodontol,2019,23(5):436-441.

Clinical effect and patients’ satisfaction evaluation of platelet rich fibrin in treatment of gingival recession

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