›› 2021, Vol. 41 ›› Issue (7): 664-668.

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Research progress of exosome functions in salivary adenoid cystic carcinoma

  

  • Received:2020-08-03 Revised:2020-08-31 Online:2021-07-28 Published:2021-07-28

Abstract: Salivary adenoid cystic carcinoma (SACC) is a common clinical malignancy of salivary glands. The tumor tends to grow slowly, has a highly neurotropic character, is aggressive and easily invades blood vessels, leading to hematogenous metastasis. In recent years, some advances have been made in the study of the pathogenesis and molecular phenotype of the disease. With the application of various in vitro experimental methods, researchers have gradually realized that exosomes play an important role in the proliferation, migration and invasion of solid tumors. It is of great significance to further explore the function of exosomes in adenoid cystic carcinoma, which can open up new ideas for research on the pathogenesis of adenoid cystic carcinoma.

Key words: exosomes, salivary adenoid cystic carcinoma, proliferation, perineural invasion, angiogenesis

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