Abstract: Silk fibroin (SF), as a natural polymer fiber protein, has been used as an ideal dressing in oral maxillofacial and whole skin wound repairing. Although SF has good biocompatibility, degradability, mechanical properties and the ability to promote healing, it does not possess antibacterial properties. Various antibacterial modifications to impart antibacterial properties to SF materials have received extensive research and attention. This article systematically introduces the applications of SF antibacterial modification materials in skin tissue engineering, thus to provide ideas and guidance for future research on SF antibacterial scaffold materials.

Key words: silk fibroin, antibacterial modification, skin tissue engineering