Abstract: [Abstract] Objective To investigate the effectiveness of fluoride-releasing orthodontic bonding cements on preventing enamel demineralization around brackets during orthodontic treatment. Methods A total of 24 participants were included. All the teeth were divided into two groups: the one side of teeth were applied with resin modified glass ionomer(GC), while the contralateral teeth were assigned to receive resin bonding system including self-ecthing primer(Transbond). DIGNOdent were uesed immediately，after three months and six months after bonding to observe the possible demineralization．EDI index and the detection rate of white spot lesion were recorded to evaluate enamel demineralization situation．Results There were no significant difference among two groups regarding EDI index , DD and WSL before and after 3 months orthodontic treatment. The data indicated a significant 1ower EDI, DD and WSL in the GC group than in the Transbond group(P<0.05) after six months. Conclusions Both of two fluoride-releasing bonding system can reduce the demineralization ,but resin modified ionomer has the better long-term.

Key words: fluoride releasing, enamel demineralization, orthodontic treatment