Abstract: Objective: To evaluate the application of harmonic Scalpel in radical forearm free flap harvesting surgery. Methods: From August 2014 to December 2015, 26 patients were accepted radical forearm free flap harvesting surgery. They were divided into two groups, the treatment group was treated with harmonic Scalpel.the control group was treated with conventional scalpel. The operation time ,intraoperative bleeding volume and surgical complication were recorded. Results:All radical forearm free flaps survive. Operative time of the treatment group was significantly less then the control group（P＜0.05）, The intraoperative bleeding volume of the treatment group was obviously less than the control group（P＜0.05）. No complications occured. Conclusion:Harmonic Scalpel using can significantly reduce the operation time and intraoperative bleed loss volume. It is worth of clinical promotion.

Key words: harmonic Scalpel, radical forearm free flap, operative time, bleeding volume