口腔医学 ›› 2025, Vol. 45 ›› Issue (6): 412-417.doi: 10.13591/j.cnki.kqyx.2025.06.003

• 基础与临床研究 • 上一篇    下一篇

Er:YAG激光与再矿化剂联合应用对牙釉质抗酸性能的影响

唐敏, 蒋备战()   

  1. 上海市同济口腔医院儿童口腔科,同济大学口腔医学院,上海牙组织修复与再生工程技术研究中心,同济大学口腔医学研究所,上海(200072)
  • 收稿日期:2025-02-10 出版日期:2025-06-28 发布日期:2025-07-08
  • 通讯作者: 蒋备战 E-mail: jiangbeizhan@tongji.edu.cn
  • 基金资助:
    上海市卫生健康委员会科研项目(202140357);上海申康医院发展中心新兴前沿技术联合攻关项目(SHDC12023115)

Effect of combined application of Er: YAG laser and remineralizers on enamel acid resistance

TANG Min, JIANG Beizhan()   

  1. Shanghai Engineering Research Center of Tooth Restoration and Regeneration & Tongji Research Institute of Stomatology & Department of Pediatric Dentistry, Shanghai Tongji Stomatological Hospital and Dental School, Tongji University, Shanghai 200072, China
  • Received:2025-02-10 Online:2025-06-28 Published:2025-07-08

摘要:

目的 评估掺铒钇铝石榴石(erbium-doped:yttrium aluminum garnet,Er:YAG)激光与再矿化剂联合应用对牙釉质抗酸性能的影响。方法 取因正畸需要拔除的健康牙齿,按统一标准制备60份牙釉质块,随机分为6组(n=10),分别经去离子水(A组)、氟化钠(B组)、生物活性玻璃(C组)、Er:YAG激光(D组)、Er:YAG激光联合氟化钠(E组)、Er:YAG激光联合生物活性玻璃(F组)连续处理7 d后,进行pH循环脱矿。实验结束后,检测各组牙釉质表面形貌、钙/磷比、表面硬度以及表面粗糙度。结果 ①表面形貌:A~F组牙釉质表面均有不同程度的破坏,其中E、F组破坏程度最小,A组凹陷缺损最明显。②钙/磷比:B、C、D组牙釉质表面的钙/磷比显著高于A组(P<0.000 1),B、C、D组组间两两比较无明显差异(P>0.05),E、F组牙釉质表面的钙/磷比显著高于B、C、D组(P<0.00 1)。③表面硬度:经酸蚀脱矿后,各组牙釉质表面硬度均降低。B、C、D组牙釉质表面硬度损失量显著低于A组(P<0.000 1),B、C、D组组间两两比较无显著差异(P>0.05),E、F组牙釉质表面硬度损失量显著低于B、C、D组(P<0.001)。④表面粗糙度:与A组相比,D组牙釉质表面粗糙度降低,但无统计学意义(P>0.05),B、C组显著降低(P<0.000 1),B、C组组间比较差异无统计学意义(P>0.05),E、F组牙釉质表面粗糙度显著低于B、C、D组(P<0.001)。结论 Er:YAG激光与再矿化剂联合应用可增强牙釉质的抗酸性能,这为牙酸蚀症的治疗提供了新的参考。

关键词: Er:YAG激光, 再矿化剂, 抗酸性能, 牙酸蚀症

Abstract:

Objective To evaluate the effect of Er: YAG(erbium-doped: yttrium aluminum garnet)laser combined with remineralizers on enamel acid resistance. Methods Healthy teeth that needed to be extracted due to orthodontic treatment were included, and 60 enamel blocks according to a unified standardwere prepared, and randomly divided into 6 groups(n=10). They were treated with deionized water(Group A), sodium fluoride(Group B), bioactive glass(Group C), Er: YAG laser(Group D), Er: YAG laser combined with sodium fluoride(Group E), and Er: YAG laser combined with bioactive glass(Group F)for 7 consecutive days before undergoing pH cycling demineralization. After the experiment, the surface morphology, calcium/phosphorus ratio, surface hardness, and surface roughness were measured in each group. Results ①Surface morphology: the enamel surfaces of groups A-F were all damaged to varying degrees, with groups E and F showing the least degree of damage, while group A had obvious concave defects. ②Calcium/phosphorus ratio: the calcium/phosphorus ratio on the enamel surface of groups B,C and D was significantly higher than that of group A(P<0.000 1), while there was no significant difference between groups B,C and D(P>0.05). The calcium/phosphorus ratio on the enamel surface of groups E and F was significantly higher than that of groups B,C and D(P<0.001). ③Surface hardness: after acid etching, the surface hardness of enamel in all groups decreased. The surface hardness loss of enamel in groups B,C and D was significantly lower than that in group A(P<0.000 1), while there was no significant difference between groups B,C and D(P>0.05). The surface hardness loss of enamel in groups E and F was significantly lower than that in groups B,C and D(P<0.001). ④Surface roughness: Compared with group A, the surface roughness of enamel in group D was reduced, but not statistically significant(P>0.05). Groups B and C showed a significant decrease(P<0.000 1), while there was no significant difference between groups B and C(P>0.05). The surface roughness of enamel in groups E and F was significantly lower than that in groups B,C and D(P<0.001). Conclusion The combined application of Er: YAG laser and remineralizers can enhance the acid resistance of enamel, providing a new reference for the treatment of dental erosion.

Key words: Er:YAG laser, remineralizer, acid resistance, dental erosion

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